shop

店(みせ) A shop, speaking generally. “I got to go open the shop now.” (The speaker can use this no matter what kind of shop it is).
 
屋(や) Store – usually used for stores that only sell one thing:fish store(魚屋), book store(本屋), used clothes store(古着屋), bakery パン屋.   $$$
 
店舗(~てんぼ) Branch of a chain store.