obstacle

阻害(そがい)	A physical obstacle (a tree in the road) 阻害物 (そがいぶつ).

妨害(ぼうがい)	Interference. (Used with people, not objects like 阻害 (そがい).)

支障(ししょう)	An obstacle to a plan: “There were so many obstacles we had to overcome to arrange this wedding – finding the right venue, getting affordable silverware, trying to find a band that knew how to play ‘ace of spades,’ etc.”

足手まとい(あしでまとい)	A weak link: A person who holds back the team. PPP